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So, while the idea that B12 injections cause weight gain might be a popular rumor, current evidence indicates that a vitamin B12 deficiency is unlikely to affect your weight directly in terms of gain

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Injecting it directly into a vein causes osmotic pressure to draw fluid into red blood cells, causing them to rupture (hemolysis)

We will use the Bayley-III scores at 6 and 12 months in separate analyses where B 12 supplementation is the main exposure

Particularly relevant for athletes and active individuals prioritizing functional recovery over just anatomical healing